If you are taking this drug on an "as needed" basis (not on a regular schedule), remember that pain medications work best if they are used as the first signs of pain occur. This medication usually should not be taken for more than 7 days at a time. Do not increase your dose, take it more frequently, or take it for a longer time than prescribed. To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Certain antacids may change the amount of mefenamic acid absorbed by the body.ĭosage is based on your medical condition and response to therapy. Do not take mefenamic acid with antacids unless directed by your doctor. If stomach upset occurs, take this medication with food or milk. Do not lie down for at least 10 minutes after taking this drug. Take this medication by mouth, usually 4 times a day with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. If you have any questions, consult your doctor or pharmacist. Read the Medication Guide provided by your pharmacist before you start using mefenamic acid and each time you get a refill. Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication. ![]() Stop taking this medication and seek immediate medical attention if you notice any of the following rare but very serious side effects: chest pain, severe dizziness, trouble breathing, weakness on one side of the body, sudden vision changes, trouble speaking, black stools, persistent stomach/ abdominal pain, vomit that looks like coffee grounds. This bleeding can occur without warning symptoms at any time during treatment. Also, this drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. ![]() Do not take this drug right before or after heart bypass surgery (CABG). The risk may be greater in older adults or if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes). (See Drug Interactions section.) This effect can happen at any time while taking this drug but is more likely if you take it for a long time. This effect does not apply to low-dose aspirin. Nonsteroidal anti-inflammatory drugs (including mefenamic acid) may rarely increase the risk for a (sometimes fatal) heart attack or stroke.
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